Oncolytic mineralized bacteria as potent locally administered immunotherapeutics

Nature Biomedical Engineering, Published online: 21 March 2024; doi:10.1038/s41551-024-01191-wIntratumourally administered bacteria coated with manganese dioxide modulate the immunosuppressive tumour microenvironment and potently activ…

Nature Biomedical Engineering, Published online: 21 March 2024; doi:10.1038/s41551-024-01191-w

Intratumourally administered bacteria coated with manganese dioxide modulate the immunosuppressive tumour microenvironment and potently activate antitumour immune responses, as shown in multiple solid tumours in small animals.