Boosting CAR-T cell therapies from under the skin

Boosting CAR-T cell therapies from under the skin

NIBIB in the News

clehmann

Thu, 06/13/2024 – 14:28

A research team at the Wyss Institute for Biologically Inspired Engineering at Harvard University and Harvard J…

Boosting CAR-T cell therapies from under the skin

clehmann

A research team at the Wyss Institute for Biologically Inspired Engineering at Harvard University and Harvard John A. Paulson School of Engineering and Applied Sciences (SEAS) has developed a simple intervention to help treat specific cancer cells.  A biodegradable scaffold material studied in a mouse model was locally injected under the skin and used to restimulate CAR-T cells that were administered to increase their therapeutic effect. Source: Wysss Institute at Harvard University. 

AI-powered simulation training improves human performance in robotic exoskeletons

AI-powered simulation training improves human performance in robotic exoskeletons

NIBIB in the News

clehmann

Thu, 06/13/2024 – 09:59

Researchers at North Carolina State University have demonstrated a new method t…

AI-powered simulation training improves human performance in robotic exoskeletons

clehmann

Researchers at North Carolina State University have demonstrated a new method that leverages artificial intelligence (AI) and computer simulations to train robotic exoskeletons to autonomously help users save energy while walking, running and climbing stairs. Source: NC State University 

The advent of human-assisted peer review by AI

Nature Biomedical Engineering, Published online: 12 June 2024; doi:10.1038/s41551-024-01228-0The Internet didn’t disrupt academic publishing. Audiovisual generative AI might do.

Nature Biomedical Engineering, Published online: 12 June 2024; doi:10.1038/s41551-024-01228-0

The Internet didn’t disrupt academic publishing. Audiovisual generative AI might do.

NIH collaborates with diagnostics manufacturers on obtaining authorization of multiplex tests

NIH collaborates with diagnostics manufacturers on obtaining authorization of multiplex tests

Science Highlights

raymond.macdougall

Tue, 06/11/2024 – 16:32

To date, nine medical device developers participating in the …

NIH collaborates with diagnostics manufacturers on obtaining authorization of multiplex tests

raymond.macdougall

To date, nine medical device developers participating in the RADx® Tech Independent Test Assessment Program have received emergency use authorization for at-home and point-of care test products that simultaneously detect COVID-19 and flu A/B.

Researchers create skin-inspired sensory robots to provide medical treatment

Researchers create skin-inspired sensory robots to provide medical treatment

NIBIB in the News

clehmann

Tue, 06/11/2024 – 09:14

Scientists at the University of North Carolina at Chapel Hill have created innovative so…

Researchers create skin-inspired sensory robots to provide medical treatment

clehmann

Scientists at the University of North Carolina at Chapel Hill have created innovative soft robots equipped with electronic skins and artificial muscles, allowing them to sense their surroundings and adapt their movements in real-time. These features make soft sensory robots highly adaptable and useful for enhancing medical diagnostics and treatments.  Source: UNC Chapel Hill 

Author Correction: An injectable subcutaneous colon-specific immune niche for the treatment of ulcerative colitis

Nature Biomedical Engineering, Published online: 11 June 2024; doi:10.1038/s41551-024-01232-4Author Correction: An injectable subcutaneous colon-specific immune niche for the treatment of ulcerative colitis

Nature Biomedical Engineering, Published online: 11 June 2024; doi:10.1038/s41551-024-01232-4

Author Correction: An injectable subcutaneous colon-specific immune niche for the treatment of ulcerative colitis

Deep-learning-enabled antibiotic discovery through molecular de-extinction

Nature Biomedical Engineering, Published online: 11 June 2024; doi:10.1038/s41551-024-01201-xDeep learning can be used to mine the proteomes of all available extinct organisms for the discovery of compounds with antibiotic properties.

Nature Biomedical Engineering, Published online: 11 June 2024; doi:10.1038/s41551-024-01201-x

Deep learning can be used to mine the proteomes of all available extinct organisms for the discovery of compounds with antibiotic properties.

Improved prime editing system makes gene-sized edits in human cells at therapeutic levels

Improved prime editing system makes gene-sized edits in human cells at therapeutic levels

NIBIB in the News

clehmann

Mon, 06/10/2024 – 09:20

Scientists at the Broad Institute of MIT and Harvard have improved a gene-e…

Improved prime editing system makes gene-sized edits in human cells at therapeutic levels

clehmann

Scientists at the Broad Institute of MIT and Harvard have improved a gene-editing technology that is now capable of inserting or substituting entire genes in the genome in human cells efficiently enough to be potentially useful for therapeutic applications. Source: The Broad Institute 

Efficient site-specific integration of large genes in mammalian cells via continuously evolved recombinases and prime editing

Nature Biomedical Engineering, Published online: 10 June 2024; doi:10.1038/s41551-024-01227-1Recombinases generated by phage-assisted evolution enhance the efficiency of the prime-editing-assisted targeted integration of large genes in…

Nature Biomedical Engineering, Published online: 10 June 2024; doi:10.1038/s41551-024-01227-1

Recombinases generated by phage-assisted evolution enhance the efficiency of the prime-editing-assisted targeted integration of large genes in mammalian cells.

Folic acid-mediated hollow \(\text {Mn}_{3}\text {O}_{4}\) nanocomposites for in vivo MRI/FLI monitoring the metastasis of gastric cancer

Metastasis is one of the main factors leading to the high mortality rate of gastric cancer. The current monitoring methods are not able to accurately monitor gastric cancer metastasis.

Metastasis is one of the main factors leading to the high mortality rate of gastric cancer. The current monitoring methods are not able to accurately monitor gastric cancer metastasis.