Mapping tissue heterogeneity in solid tumours using PET–MRI and machine learning

Nature Biomedical Engineering, Published online: 05 June 2023; doi:10.1038/s41551-023-01046-wDemultiplexing PET–MRI data of solid tumours using machine learning allows the spatial characterization of intratumour tissue heterogeneity in…

Nature Biomedical Engineering, Published online: 05 June 2023; doi:10.1038/s41551-023-01046-w

Demultiplexing PET–MRI data of solid tumours using machine learning allows the spatial characterization of intratumour tissue heterogeneity in mice and humans. Predicted maps of tissue subtypes within the tumour could aid in conducting image-guided biopsies and provide valuable insights linking the outcome of cancer therapies with phenotypic heterogeneity.

Quantification of intratumoural heterogeneity in mice and patients via machine-learning models trained on PET–MRI data

Nature Biomedical Engineering, Published online: 05 June 2023; doi:10.1038/s41551-023-01047-9Intratumoural heterogeneity can be characterized spatially in patients with liver metastases from colorectal cancer via phenotype-specific mul…

Nature Biomedical Engineering, Published online: 05 June 2023; doi:10.1038/s41551-023-01047-9

Intratumoural heterogeneity can be characterized spatially in patients with liver metastases from colorectal cancer via phenotype-specific multi-view learning models trained with PET–MRI data from mice with subcutaneous colon tumours.

How the combination of advanced ultrasound and AI could upgrade cancer diagnostics

How the combination of advanced ultrasound and AI could upgrade cancer diagnostics

Science Highlights

jgriffin

Fri, 06/02/2023 – 10:04

Researchers have shown that an automated cancer diagnostic method, which pairs cut…

How the combination of advanced ultrasound and AI could upgrade cancer diagnostics

jgriffin Fri, 06/02/2023 - 10:04
Researchers have shown that an automated cancer diagnostic method, which pairs cutting-edge ultrasound techniques with artificial intelligence, can accurately diagnose thyroid cancer, of which there are more than 40,000 new cases every year.

Proof of concept of an accelerometer as a trigger for unilateral diaphragmatic pacing: a porcine model

Unilateral diaphragmatic paralysis in patients with univentricular heart is a known complication after pediatric cardiac surgery. Because diaphragmatic excursion has a significant influence on perfusion of the…

Unilateral diaphragmatic paralysis in patients with univentricular heart is a known complication after pediatric cardiac surgery. Because diaphragmatic excursion has a significant influence on perfusion of the...

Brain imaging is on the move with wearable scanning development

Brain imaging is on the move with wearable scanning development

NIBIB in the News

kolsen

Tue, 05/30/2023 – 13:54

New research has demonstrated that a wearable brain scanner can measure brain function whilst people are …

Brain imaging is on the move with wearable scanning development

kolsen Tue, 05/30/2023 - 13:54
New research has demonstrated that a wearable brain scanner can measure brain function whilst people are standing and walking around. This breakthrough could help better understand and diagnose a range of neurological problems that affect movement, including Parkinson's Disease, stroke and concussion. Source: University of Nottingham/Science Daily

Induction of a torpor-like state with ultrasound

Induction of a torpor-like state with ultrasound

NIBIB in the News

kolsen

Tue, 05/30/2023 – 13:43

Researchers induced a hibernation-like state in mice by using ultrasound to stimulate the hypothalamus preoptic area in …

Induction of a torpor-like state with ultrasound

kolsen Tue, 05/30/2023 - 13:43
Researchers induced a hibernation-like state in mice by using ultrasound to stimulate the hypothalamus preoptic area in the brain, which helps to regulate body temperature and metabolism. The findings show the first noninvasive and safe method to induce such a state; a similar condition has been previously proposed for spaceflight or for patients with life-threatening health conditions. Source: Washington University in St. Louis/Science Daily

A YOLO-based AI system for classifying calcifications on spot magnification mammograms

Use of an AI system based on deep learning to investigate whether the system can aid in distinguishing malignant from benign calcifications on spot magnification mammograms, thus potentially reducing unnecessa…

Use of an AI system based on deep learning to investigate whether the system can aid in distinguishing malignant from benign calcifications on spot magnification mammograms, thus potentially reducing unnecessa...

Biomechanics of open-globe injury: a review

Open-globe injury is a common cause of blindness clinically caused by blunt trauma, sharp injury, or shock waves, characterised by rupture of the cornea or sclera and exposure of eye contents to the environmen…

Open-globe injury is a common cause of blindness clinically caused by blunt trauma, sharp injury, or shock waves, characterised by rupture of the cornea or sclera and exposure of eye contents to the environmen...

A comparison of point-tracking algorithms in ultrasound videos from the upper limb

Tracking points in ultrasound (US) videos can be especially useful to characterize tissues in motion. Tracking algorithms that analyze successive video frames, such as variations of Optical Flow and Lucas–Kana…

Tracking points in ultrasound (US) videos can be especially useful to characterize tissues in motion. Tracking algorithms that analyze successive video frames, such as variations of Optical Flow and Lucas–Kana...

A giant leap forward in wireless ultrasound monitoring for subjects in motion

A giant leap forward in wireless ultrasound monitoring for subjects in motion

NIBIB in the News

kolsen

Tue, 05/23/2023 – 09:58

Engineers have developed the first fully integrated wearable ultrasound system for deep-tis…

A giant leap forward in wireless ultrasound monitoring for subjects in motion

kolsen Tue, 05/23/2023 - 09:58
Engineers have developed the first fully integrated wearable ultrasound system for deep-tissue monitoring, including for subjects on the go. Source: University of California - San Diego/Science Daily