Nature Biomedical Engineering, Published online: 19 April 2024; doi:10.1038/s41551-024-01194-7The hydrophobicity, electrostatic charge and secondary conformation of helical polypeptides can be optimized to stimulate antitumour innate i…
The hydrophobicity, electrostatic charge and secondary conformation of helical polypeptides can be optimized to stimulate antitumour innate immune responses via endoplasmic reticulum stress in antigen-presenting cells.
Computed tomography (CT) is an imaging modality commonly used for studies of internal body structures and very useful for detailed studies of body composition. The aim of this study was to develop and evaluate…
Computed tomography (CT) is an imaging modality commonly used for studies of internal body structures and very useful for detailed studies of body composition. The aim of this study was to develop and evaluate...
NIBIB-supported researchers have developed a smart nanoprobe designed to infiltrate prostate tumors and send back a signal using an optical imaging technique known as Raman spectroscopy. The new probe, evaluated in mice, has the potential to determine tumor aggressiveness and could also enable sequential monitoring of tumors during therapy to quickly determine if a treatment strategy is working.
The timely identification and management of ovarian cancer are critical determinants of patient prognosis. In this study, we developed and validated a deep learning radiomics nomogram (DLR_Nomogram) based on u…
The timely identification and management of ovarian cancer are critical determinants of patient prognosis. In this study, we developed and validated a deep learning radiomics nomogram (DLR_Nomogram) based on u...
Nature Biomedical Engineering, Published online: 08 April 2024; doi:10.1038/s41551-024-01197-4The densities of blood vessels and of tumour-associated macrophages are key predictive features of the degree of accumulation of polymeric an…
The densities of blood vessels and of tumour-associated macrophages are key predictive features of the degree of accumulation of polymeric and liposomal nanomedicines, as shown for specimens of mouse and human tumours.
Severely damaged peripheral nerves will regenerate incompletely due to lack of directionality in their regeneration, leading to loss of nerve function. To address this problem, various nerve guidance conduits …
Severely damaged peripheral nerves will regenerate incompletely due to lack of directionality in their regeneration, leading to loss of nerve function. To address this problem, various nerve guidance conduits ...
NIBIB is marking the 10-year anniversary of a commercialization program that helps innovators bring their medical devices from the lab to the marketplace.
Nature Biomedical Engineering, Published online: 02 April 2024; doi:10.1038/s41551-024-01203-9Publisher Correction: Bacteria-mediated resistance of neutrophil extracellular traps to enzymatic degradation drives the formation of dental …
Nature Biomedical Engineering, Published online: 02 April 2024; doi:10.1038/s41551-024-01200-yAuthor Correction: Optogenetic stimulation of vagal nerves for enhanced glucose-stimulated insulin secretion and β cell proliferation