Directing vaccines to dendritic cells

Science Highlights

kolsen

Thu, 10/12/2023 – 12:22

Dendritic cells are key orchestrators of the immune response, but most vaccination strategies don’t effectively target them. NIBIB…

Directing vaccines to dendritic cells

Science Highlights

kolsen Thu, 10/12/2023 - 12:22

Dendritic cells are key orchestrators of the immune response, but most vaccination strategies don’t effectively target them. NIBIB-funded researchers have developed biodegradable nanoparticles that are designed to deliver mRNA cargo to dendritic cells in the spleen. Combined with another type of immunotherapy, their vaccine had robust antitumor effects in multiple mouse models.

Bioengineering breakthrough increases DNA detection sensitivity by 100 times

NIBIB in the News

kolsen

Wed, 10/11/2023 – 12:02

Researchers have pushed forward the boundaries of biomedical engineering one hundredfold wit…

Bioengineering breakthrough increases DNA detection sensitivity by 100 times

NIBIB in the News

kolsen Wed, 10/11/2023 - 12:02

Researchers have pushed forward the boundaries of biomedical engineering one hundredfold with a new method for DNA detection with unprecedented sensitivity. Source: University of Massachusetts Amherst/Science Daily

Scientists successfully maneuver robot through living lung tissue

NIBIB in the News

kolsen

Fri, 09/22/2023 – 10:04

Scientists have shown that their steerable lung robot can autonomously maneuver the intricacies of the …

Scientists successfully maneuver robot through living lung tissue

NIBIB in the News

kolsen Fri, 09/22/2023 - 10:04

Scientists have shown that their steerable lung robot can autonomously maneuver the intricacies of the lung, while avoiding important lung structures. Source: University of North Carolina Health Care/Science Daily

PS gene-editing shown to restore neural connections lost in brain disorder

NIBIB in the News

kolsen

Tue, 08/22/2023 – 12:41

A new study has demonstrated the ability for gene therapy to repair neural connections for tho…

PS gene-editing shown to restore neural connections lost in brain disorder

NIBIB in the News

kolsen Tue, 08/22/2023 - 12:41

A new study has demonstrated the ability for gene therapy to repair neural connections for those with the rare genetic brain disorder known as Hurler syndrome. Source: University of Minnesota Medical School/Science Daily

Hear a classic Pink Floyd song reconstructed from listeners’ brain waves

NIBIB in the News

kolsen

Thu, 08/17/2023 – 14:49

The guitar chords echo strangely, as if emanating from the bottom of a well. The singer’s voice …

Hear a classic Pink Floyd song reconstructed from listeners’ brain waves

NIBIB in the News

kolsen Thu, 08/17/2023 - 14:49

The guitar chords echo strangely, as if emanating from the bottom of a well. The singer’s voice is also garbled, his lyrics barely intelligible. Nevertheless, if you know what’s coming, the song is recognizable: “All in all, it was just a brick in the wall.” It’s a snippet of “Another Brick in the Wall (Part 1)” from the album “The Wall,” which was a smash hit in 1979 for the U.K. rock band Pink Floyd. And it was re-created from brain recordings from people who listened to it. The reconstructed tune provides new insights into where in the brain music is processed. Source: Science

Scientists Recreate Pink Floyd Song by Reading Brain Signals of Listeners

NIBIB in the News

kolsen

Thu, 08/17/2023 – 14:43

Scientists have trained a computer to analyze the brain activity of someone listening to music …

Scientists Recreate Pink Floyd Song by Reading Brain Signals of Listeners

NIBIB in the News

kolsen Thu, 08/17/2023 - 14:43

Scientists have trained a computer to analyze the brain activity of someone listening to music and, based only on those neuronal patterns, recreate the song. The research produced a recognizable, if muffled version of Pink Floyd’s 1979 song, “Another Brick in the Wall (Part 1).” Before this, researchers had figured out how to use brain activity to reconstruct music with similar features to the song someone was listening to. Now, “you can actually listen to the brain and restore the music that person heard,” said Gerwin Schalk, a neuroscientist who directs a research lab in Shanghai and collected data for this study. Source: New York Times

Nanozymes drive tumor-specific drug delivery while minimizing toxicity

Science Highlights

kolsen

Mon, 08/07/2023 – 12:14

Nanozymes—artificial enzymes that can carry out pre-determined chemical reactions—could selective…

Nanozymes drive tumor-specific drug delivery while minimizing toxicity

Science Highlights

kolsen Mon, 08/07/2023 - 12:14

Nanozymes—artificial enzymes that can carry out pre-determined chemical reactions—could selectively activate a cancer drug within a tumor while minimizing damage to healthy tissue in a mouse model of triple negative breast cancer.

How good is that AI-penned radiology report?

NIBIB in the News

kolsen

Mon, 08/07/2023 – 10:29

New study identifies concerning gaps between how human radiologists score the accuracy of AI-generated radiology reports and…

How good is that AI-penned radiology report?

NIBIB in the News

kolsen Mon, 08/07/2023 - 10:29

New study identifies concerning gaps between how human radiologists score the accuracy of AI-generated radiology reports and how automated systems score them. Researchers designed two novel scoring systems that outperform current automated systems that evaluate the accuracy of AI narrative reports. Reliable scoring systems that accurately gauge the performance of AI models are critical for ensuring that AI continues to improve and that clinicians can trust them. Source: Harvard Medical School/Science Daily

New software designs optimized, personalized treatments for movement impairments

Grantee News

kolsen

Mon, 07/31/2023 – 14:33

A team of Rice University engineers has launched a first of its kind, open-source software th…

New software designs optimized, personalized treatments for movement impairments

Grantee News

kolsen Mon, 07/31/2023 - 14:33

A team of Rice University engineers has launched a first of its kind, open-source software that constructs and uses personalized computer models of how individual patients move to optimize treatments for neurologic and orthopedic mobility impairments. Source: Rice University

Wireless wonder: wearable ultrasound patch goes completely cable-free

Science Highlights

kolsen

Thu, 07/06/2023 – 15:30

This fully wireless ultrasound patch, which can capture detailed medical information and wirelessl…

Wireless wonder: wearable ultrasound patch goes completely cable-free

Science Highlights

kolsen Thu, 07/06/2023 - 15:30

This fully wireless ultrasound patch, which can capture detailed medical information and wirelessly transmit the data to a smart device, could represent a major step forward in at-home health care technology.