Smart nanoprobe illuminates prostate cancer cells

Science Highlights

kolsen

Thu, 04/11/2024 – 09:35

NIBIB-supported researchers have developed a smart nanoprobe designed to infiltrate prostate tumors and send back a s…

Smart nanoprobe illuminates prostate cancer cells

kolsen Thu, 04/11/2024 - 09:35

NIBIB-supported researchers have developed a smart nanoprobe designed to infiltrate prostate tumors and send back a signal using an optical imaging technique known as Raman spectroscopy. The new probe, evaluated in mice, has the potential to determine tumor aggressiveness and could also enable sequential monitoring of tumors during therapy to quickly determine if a treatment strategy is working.

A window into placental development during pregnancy

Science Highlights

kolsen

Tue, 03/19/2024 – 12:54

A multidisciplinary group of NIH-funded scientists have successfully captured real-time, high-resolution images of …

A window into placental development during pregnancy

Science Highlights

kolsen Tue, 03/19/2024 - 12:54

A multidisciplinary group of NIH-funded scientists have successfully captured real-time, high-resolution images of the developing mouse placenta during the course of pregnancy. Their technique, which combines a surgically implanted window with a next-generation imaging system, provides key insight into placental development under both healthy and pathological conditions.

Synthetic Circuits Reveal the Key to Rewinding the Cellular Clock

NIBIB in the News

kolsen

Thu, 03/14/2024 – 09:46

Using a circuit-based system, scientists determined the ideal transcription factor levels to promote th…

Synthetic Circuits Reveal the Key to Rewinding the Cellular Clock

NIBIB in the News

kolsen Thu, 03/14/2024 - 09:46

Using a circuit-based system, scientists determined the ideal transcription factor levels to promote the successful reprogramming of fibroblasts into induced pluripotent stem cells.

Engineered bacteria prime tumors for selective elimination

Science Highlights

kolsen

Fri, 03/01/2024 – 10:36

What if bacteria—which love to grow deep inside tumors—could guide cancer therapies directly to their target?…

Engineered bacteria prime tumors for selective elimination

Science Highlights

kolsen Fri, 03/01/2024 - 10:36

What if bacteria—which love to grow deep inside tumors—could guide cancer therapies directly to their target? NIH-funded researchers have engineered a bacterial strain to “light up” tumors so that reprogrammed T cells, drawn like a moth to a flame, can find and destroy them. Their preclinical treatment could potentially be effective against any solid tumor type.

Bypassing the blood-brain barrier to improve brain tumor diagnosis

Science Highlights

kolsen

Mon, 02/26/2024 – 11:12

A collaborative team of NIH-funded researchers is developing a way to obtain DNA shed from brain tumo…

Bypassing the blood-brain barrier to improve brain tumor diagnosis

Science Highlights

kolsen Mon, 02/26/2024 - 11:12

A collaborative team of NIH-funded researchers is developing a way to obtain DNA shed from brain tumors using focused ultrasound. Their first-in-human study could be an important step towards improving the way brain tumors are diagnosed.

Preventing severe allergic reactions with nanoparticles

NIBIB in the News

kolsen

Tue, 02/06/2024 – 16:26

NIH-funded researchers created nanoparticles that could deactivate immune cells and prevent severe allergic react…

Preventing severe allergic reactions with nanoparticles

NIBIB in the News

kolsen Tue, 02/06/2024 - 16:26

NIH-funded researchers created nanoparticles that could deactivate immune cells and prevent severe allergic reactions in mice. The findings could lead to new approaches to prevent allergies and anaphylaxis in people. Source: NIH Research Matters

New Vibrating Pill May Be A Cost Effective Option To Aid Weight Loss, Study Finds

NIBIB in the News

kolsen

Wed, 12/27/2023 – 09:46

A first-of-its-kind vibrating pill that significantly reduces food consumption by mimic…

New Vibrating Pill May Be A Cost Effective Option To Aid Weight Loss, Study Finds

NIBIB in the News

kolsen Wed, 12/27/2023 - 09:46

A first-of-its-kind vibrating pill that significantly reduces food consumption by mimicking the feeling of fullness was crafted by researchers at the Massachusetts Institute of Technology, and they believe the pill can be used as a cheaper, noninvasive option to treat obesity and other weight-related illnesses. Source: Forbes

Getting under your skin: 3D printing technique builds structures through tissues

Science Highlights

kolsen

Wed, 12/06/2023 – 15:55

NIH-funded researchers have outlined a method to print biocompatible structures throug…

Getting under your skin: 3D printing technique builds structures through tissues

Science Highlights

kolsen Wed, 12/06/2023 - 15:55

NIH-funded researchers have outlined a method to print biocompatible structures through thick, multi-layered tissues using focused ultrasound.

Breast cancer cells collaborate to break free and invade into the surrounding tissue

Grantee News

kolsen

Tue, 11/14/2023 – 13:23

Researchers at Stanford revealed a novel physical mechanism that breast cancer cells use …

Breast cancer cells collaborate to break free and invade into the surrounding tissue

Grantee News

kolsen Tue, 11/14/2023 - 13:23

Researchers at Stanford revealed a novel physical mechanism that breast cancer cells use to break out and become invasive. They found that, in addition to established chemical methods of degrading the basement membrane, cancer cells work as a group to physically deform and tear through the basement membrane barrier. Source: Stanford News

Directing vaccines to dendritic cells

Science Highlights

kolsen

Thu, 10/12/2023 – 12:22

Dendritic cells are key orchestrators of the immune response, but most vaccination strategies don’t effectively target them. NIBIB…

Directing vaccines to dendritic cells

Science Highlights

kolsen Thu, 10/12/2023 - 12:22

Dendritic cells are key orchestrators of the immune response, but most vaccination strategies don’t effectively target them. NIBIB-funded researchers have developed biodegradable nanoparticles that are designed to deliver mRNA cargo to dendritic cells in the spleen. Combined with another type of immunotherapy, their vaccine had robust antitumor effects in multiple mouse models.