A serine-conjugated butyrate prodrug with high oral bioavailability suppresses autoimmune arthritis and neuroinflammation in mice

Nature Biomedical Engineering, Published online: 01 April 2024; doi:10.1038/s41551-024-01190-xThe esterification of butyrate to serine makes for an odourless and tasteless oral prodrug that ameliorated disease severity and reduced infl…

Nature Biomedical Engineering, Published online: 01 April 2024; doi:10.1038/s41551-024-01190-x

The esterification of butyrate to serine makes for an odourless and tasteless oral prodrug that ameliorated disease severity and reduced inflammatory responses in mouse models of rheumatoid arthritis and multiple sclerosis.